Searchable abstracts of presentations at key conferences in endocrinology

ea0049gp10 | Adrenal 1 | ECE2017

Expression of GATA transcription factors and their role in the aetiology of Testicular Adrenal Rest Tumours

Engels Manon , Span Paul , Marijnissen-van Zanten Monica , van Herwaarden Teun , Hulsbergen-van de Kaa Christina , Mitchell Rod , Smith Lee , Stikkelbroeck Nike , Sweep Fred , Claahsen-van der Grinten Hedi

Background: Recently, GATA transcription factors have been linked to the development of Testicular Adrenal Rest Tumours (TART), benign adrenal-like testicular tumours that frequently occur in male patients with congenital adrenal hyperplasia (CAH). The objective of this study is to determine GATA expression in TART and other steroidogenic tissues, examining their discriminative potential and their possible role in the aetiology of TART.Methods: GATA1-6 e...